Russell Broaddus, M.D., Ph.D.

I am a tenured Professor with expertise in GI and gynecologic pathology.  I am also the Medical Director for Solid Tumor Molecular Diagnostics in the Division of Pathology & Laboratory Medicine at M.D. Anderson Cancer Center.  I am PI for one Endometrial Cancer SPORE project and PI for the Pathology Core for both the Endometrial Cancer SPORE and Ovarian Cancer SPORE.  My research lab focuses on the molecular pathogenesis of endometrial cancer, the most common gynecologic cancer in the Western world.  Current projects include developing molecular diagnostics for predicting endometrial cancer histotype and stage, developing clinical and lab-based algorithms for the identification of patients with hereditary colorectal and endometrial cancer (Lynch Syndrome), discovering novel molecular mediators of endometrial cancer invasion and metastasis, and identifying novel signaling pathways important in the pathogenesis of endometrial cancer.  In addition to my work in endometrial cancer, I have extensive experience in working with animal models of colitis and colon cancer and mouse models of gynecological tract disease, including endometrial cancer.